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1

Tocotrienol-Rich Fraction from Rice Bran Demonstrates Potent Radiation Protection Activity

Krager, Kimberly J., Pineda, E. Nathalie, Kharade, Sujay V., Kordsmeier, Mary, Howard, Luke, Breen, Philip J., Compadre, Cesar M., Hauer-Jensen, Martin, Aykin-Burns, Nukhet

Journal:

Evidence-based Complementary and Alternative Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 3.73 MB

english, 2015

2

Mrg19 depletion increases S. cerevisiae lifespan by augmenting ROS defence

Sujay V. Kharade, Nitish Mittal, Shankar P. Das, Pratima Sinha, Nilanjan Roy

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 169 KB

english, 2005

3

Cardiac and renal inward rectifier potassium channel pharmacology: emerging tools for integrative physiology and therapeutics

Swale, Daniel R, Kharade, Sujay V, Denton, Jerod S

Journal:

Current Opinion in Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 1012 KB

english, 2014

4

ROMK (Kir1.1) pharmacology comes of age

Kharade, Sujay V, Swale, Daniel R, Denton, Jerod S

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 729 KB

english, 2015

5

ROMK Inhibitor Actions in the Nephron Probed with Diuretics

Kharade, Sujay V., Flores, Daniel, Lindsley, Craig W, Satlin, Lisa M., Denton, Jerod S.

Journal:

AJP: Renal Physiology

Année:

2015

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2015

6

The shifting landscape of K ATP channelopathies and the need for ‘sharper’ therapeutics

Kharade, Sujay V, Nichols, Colin, Denton, Jerod S

Journal:

Future Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 2.98 MB

english, 2016

7

ML418: The first selective, sub-micromolar pore blocker of Kir7.1 potassium channels

Swale, Daniel R., Kurata, Haruto, Kharade, Sujay V., Sheehan, Jonathan H, Raphemot, Rene R., Voigtritter, Karl R., Figueroa, Eric, Meiler, Jens, Flobaum, Anna L., Lindsley, Craig W, Hopkins, Corey R.,

Journal:

ACS Chemical Neuroscience

Année:

2016

Langue:

english

Fichier:

PDF, 2.25 MB

english, 2016

8

BK Channels in Rat and Human Pulmonary Smooth Muscle Cells are BK α-β 1 Functional Complexes Lacking the Oxygen-Sensitive Stress Axis Regulated Exon Insert

Detweiler, Neil D., Song, Li, McClenahan, Samantha J., Versluis, Rachel J., Kharade, Sujay V., Kurten, Richard C., Rhee, Sung W., Rusch, Nancy J.

Journal:

Pulmonary Circulation

Année:

2016

Langue:

english

Fichier:

PDF, 3.39 MB

english, 2016

9

Pore polarity and charge determine differential block of Kir1.1 and Kir7.1 potassium channels by the small-molecule inhibitor VU590

Kharade, Sujay, Sheehan, Jonathan, Figueroa, Eric, Meiler, Jens, Denton, Jerod

Journal:

Molecular Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 2.31 MB

english, 2017

10

Plight of the pore polar bar(rier)

Denton, Jerod S., Kharade, Sujay V.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 776 KB

english, 2017

11

Discovery and In Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors

Sammons, Matthew F., Kharade, Sujay V., Filipski, Kevin J., Boehm, Markus, Smith, Aaron C., Shavnya, Andre, Fernando, Dilinie P., Dowling, Matthew S., Carpino, Philip A, Castle, Neil A., Zellmer, Shan

Journal:

ACS Medicinal Chemistry Letters

Année:

2018

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2018

12

Discovery, characterization, and effects on renal fluid and electrolyte excretion of the Kir4.1 potassium channel pore blocker, VU0134992

Kharade, Sujay V., Kurata, Haruto, Bender, Aaron, Blobaum, Anna L., Figueroa, Eric, Duran, Amanda M., Kramer, Meghan, Days, Emily, Vinson, Paige, Flores, Daniel, Satlin, Lisa M., Meiler, Jens, Weaver,

Journal:

Molecular Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2018

13

Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-gated, Inwardly-rectifying, Potassium (GIRK) Channels

Kozek, Krystian A, Du, Yu, Sharma, Swagat, Prael, Francis J, Spitznagel, Brittany D, Kharade, Sujay V., Denton, Jerod S., Hopkins, Corey R., Weaver, C. David

Journal:

ACS Chemical Neuroscience

Année:

2018

Langue:

english

Fichier:

PDF, 866 KB

english, 2018

14

Discovery and characterization of 2-nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)-N-(pyridin-4-ylmethyl)anilines as novel inhibitors of the Aedes aegypti Kir1 (AeKir1) channel

Aretz, Christopher, Morwitzer, M Jane, Sanford, Austin, Hogan, Alicia M, Portillo, Madalene, Kharade, Sujay V, Kramer, Meghan, Mcarthey, James, Trigueros, Renata R, Piermarini, Peter M., Denton, Jerod

Journal:

ACS Infectious Diseases

Année:

2019

Fichier:

PDF, 683 KB

2019

15

Structure-activity relationships, pharmacokinetics, and pharmacodynamics of the Kir6.2/SUR1-specific channel opener, VU0071063

Kharade, Sujay V., Sanchez-Andres, Juan Vicente, Fulton, Mark G., Shelton, Elaine J., Blobaum, Anna L., Engers, Darren W., Hofmann, Christopher S., Dadi, Prasanna K., Lantier, Louise, Jacobson, David

Journal:

Journal of Pharmacology and Experimental Therapeutics

Année:

2019

Langue:

english

Fichier:

PDF, 907 KB

english, 2019

16

The LRRC8 volume‐regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel

Afzal, Aqeela, Figueroa, Eric E., Kharade, Sujay V., Bittman, Kevin, Matlock, Brittany K., Flaherty, David K., Denton, Jerod S.

Journal:

Physiological Reports

Année:

2019

Langue:

english

Fichier:

PDF, 962 KB

english, 2019

17

The LRRC8 volume‐regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel

Afzal, Aqeela, Figueroa, Eric E., Kharade, Sujay V., Bittman, Kevin, Matlock, Brittany K., Flaherty, David K., Denton, Jerod S.

Journal:

Physiological Reports

Année:

2019

Fichier:

PDF, 962 KB

2019

18

Further SAR on the (phenylsulfonyl)piperazine scaffold as inhibitors of theÂ Aedes aegyptiÂ Kir1 (AeKir) channel and larvicides

Aretz, Christopher, Kharade, Sujay V, Chronister, Keagan, Trigueros, Renata Rusconi, Rodriguez, Erick Martinez, Piermarini, Peter M, Denton, Jerod S, Hopkins, Corey R

Journal:

Année:

2020

Fichier:

PDF, 1.02 MB

2020